Matthew McConaughey plays a bag-of-bones, good ol' boy piece of sex-addled trailer trash who has the misfortune to bang the wrong (female) intravenous drug-user (HIV+) in the wrong way (sans condom) in the wrong place (darkest Texas) at the wrong time (the panicked, unmedicated '80s). Suddenly, he's cast out among those he hates, and overdosing on the only medicine out there (AZT), which nearly kills him. (The bastards at Big Pharma and the FDA, eager to cash in on the AIDS panic, are running human trials.) Eventually, he heads south of the border to visit a disgraced doctor who knows what's good for him. And what's good for Ron is good for his fellow sufferers, including Rayon, a junkie trans woman played with mesmerizing commitment by Jared Leto. So our hero starts peddling meds and making bank, and learns to love along the way. Naturally, the authorities object. With Jennifer Garner. (2013) — Matthew Lickona
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