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Stock of biotech Sequenom jumped 16.37% to $5.26 today (Feb. 16) as the company launched its fetal test for sex determination. The company says the test is noninvasive, requiring only a blood sample from the mother, and it makes the sex determination in the first trimester. Reuters points out that the test employs the company's SEQureDx technology, which had been suspended over an employee's mishandling of research and data. In April, the company shelved introduction of a Down syndrome test and said it was no longer relying on previous test data related to SEQureDx.

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Comments

SurfPuppy619 Feb. 16, 2010 @ 2:58 p.m.

Just what I needed..where can I buy one?

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Don Bauder Feb. 16, 2010 @ 4:20 p.m.

Response to post #1: It depends how many paternity suits have been filed against you. Best, Don Bauder

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Psycholizard Feb. 18, 2010 @ 2:12 p.m.

If the third world could select the sex of it's offspring, world population might actually decline, thanks to the overwhelming popularity of boys across the impoverished communities of the world. Thanks partly to abortion and fetal sex determination, China and India now have generations with more males than females. Since the traditional way is murder, I can't object on moral grounds, but the wide ranging social consequences shouldn't be ignored.

Assuming their procedure works, Sequenon might have a big market around the world, with profound effects on demographics similar to the birth control pill.

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Don Bauder Feb. 18, 2010 @ 2:17 p.m.

Response to post #3: I checked online. There are four outstanding paternity suits against our SurfPuppy. The first name of every one of the female plaintiffs is Fannie. The second name is Mae. This may explain his investment philosophy. Best, Don Bauder

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Don Bauder Feb. 18, 2010 @ 2:23 p.m.

Response to post #4: Interesting how things change. After both World War I and World War II, countries and towns throughout Europe had far more women than men because of the massive war deaths. The imbalance was particularly pronounced in Russia after World War II. Now it's going the other way. I don't know if Sequenom sees a market in China and Russia. It would be logical. Best, Don Bauder

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Don Bauder Feb. 18, 2010 @ 2:25 p.m.

NOTE ON POST #6: I meant China and India, not Russia. Best, Don Bauder

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SDaniels Feb. 18, 2010 @ 2:25 p.m.

re: #5: The kids SurfPup may have fathered are mostly girls, Sallie, Salliemae, Maesallie, Salome, and... Freddie Mac.

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Don Bauder Feb. 18, 2010 @ 2:28 p.m.

Response to post #8: As I recall, he has had nothing good to say about Sallie Mae. And now she is his daughter. Salome knows how to take care of obstreperous men. Best, Don Bauder

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Psycholizard Feb. 18, 2010 @ 4:49 p.m.

to 9

Figures that Surf Puppy would father a litter of loan documents. He only remembers compounding her once, and now she won't roll over. It's so unfair.

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Don Bauder Feb. 18, 2010 @ 6:46 p.m.

Response to post #10: S&L loan documents? Or S&M loan documents? We have not heard from SurfPuppy on this one. Best, Don Bauder

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Psycholizard Feb. 19, 2010 @ 12:39 a.m.

to 6

The test might also do well in the Moslem world, where women dislike examination by male doctors, and there are few female ones. Sequenon has a hit if it really works.

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Don Bauder Feb. 19, 2010 @ 10:20 a.m.

Response to post #12: There are other tests for sex determination, too. So there is competition. Best, Don Bauder

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Don Bauder Feb. 19, 2010 @ 4:47 p.m.

Response to post #14: You started it, SP. The first post was yours. Best, Don Bauder

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Psycholizard Feb. 20, 2010 @ 1:04 a.m.

to 13

Traditional methods are still best. Even though the hoochie coochie man, voodoo woman or witch doctor only had a 50-50 success rate, they predicted the desired sex nearly 100% of the time. This helped the lady through some difficult months.

Sometimes the truth is wrong. Consider the pregnant question; "Do I look fat?". Any man who tells the truth to his eight months pregnant wife, can and perhaps should be killed with impunity on the grounds of mental cruelty.

Best business practice for the witch doctor is to change towns regularly. Some recommend this for husbands too, but not you Surfpuppy because we would miss you.

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Duhbya Feb. 20, 2010 @ 7:47 a.m.

Doesn't the request/need for a test usually indicate that there was sex involved at some juncture? Is gender still a practicable word? By the way, the lawsuits against SurfPuppy are frivolous. He was spayed early on.

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Don Bauder Feb. 20, 2010 @ 8:13 a.m.

Response to post #16: You are talking about medical odds, as well as ruses to make patients feel better. This is why medical scams do so well. Placebos work 20 to 30% of the time. That produces a nice fat market for hucksters selling elixirs. Best, Don Bauder

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Don Bauder Feb. 20, 2010 @ 8:16 a.m.

Response to post #17: The dude was spayed? Is that why he is such a famous counter-tenor in San Diego Opera? Best, Don Bauder

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Duhbya Feb. 20, 2010 @ 9:26 a.m.

Re#19: Ha! See how confusing it can get? Of course I meant to type "neutered" - the third gender. Surf P is a counter-tenorist? Undercover, I surmise. Who knew?

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Psycholizard Feb. 20, 2010 @ 12:05 p.m.

to 18

The biotech combines two ancient forms of confidence games, medicine and the stock company, into a potent new scheme, possible now because medicine has dropped the silly old pretense of putting the patient before profit.

But scientific medicine is our best hope for a healthy life, and an equity play is better than a loan when investing in a speculative venture, because even though you risk every penny, you won't face Surfpuppy's fangs of death in bankruptcy court.

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Don Bauder Feb. 20, 2010 @ 1:24 p.m.

Response to post #20: How can you be undercover if you are singing on stage in front of 3,000 at San Diego Opera? Best, Don Bauder

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Don Bauder Feb. 20, 2010 @ 1:28 p.m.

Response to post #21: In biotech IPOs, the insiders usually pay a penny or two a share. It's a license to steal. Best, Don Bauder

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Psycholizard Feb. 20, 2010 @ 4:17 p.m.

to 22

3,000? 70,000 at the stadium for a start. There is no performance in dance, drama or music that wouldn't draw ten times more starring a dog with floppy ears. Could Milli or Vanelli sing? Is the piano playing cat any good? Surfpuppy will save opera.

He should start with the lighter stuff, The Barker of Seville, Fido Lea, mature to Tan Bowser and Ill Pug Latchkey. After saving opera, he might try theater, Oedipus Rex perhaps?

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Don Bauder Feb. 20, 2010 @ 7:54 p.m.

Response to post #24: Funny. The last opera I saw in San Diego was Tannhauser (your Tan Bowser) -- twice. It was wonderful. The last opera I saw of any kind was the Barber of Seville (your Barker). I haven't seen Fidelio (your Fido Lea) or Pagliacci (your Ill Pug Latchkey) for awhile. I congratulate you for your creativity. Best, Don Bauder

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Psycholizard Feb. 21, 2010 @ 7:58 p.m.

The idea of the dog singing opera launched me into a reverie of ideas for casting and costumes. Siegfried a rottweiler, Tosca a greyhound.. Suddenly I was awoken by a vision, direct from the Great Lizard. of flower collared dogs lip syncing Lakme'. There are things man was not meant to see.

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Duhbya Feb. 22, 2010 @ 5:26 a.m.

Re #26: More suggestions for the inaugural season? The Golden Cocker Die Fleadermaus The Saint Bernard of Bleeker Street

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Don Bauder Feb. 22, 2010 @ 6:09 a.m.

Response to post #26: How many opera singers make you think of a greyhound? Hog, yes. Greyhound, no. Best, Don Bauder

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Don Bauder Feb. 22, 2010 @ 6:28 a.m.

Response to post #27: Overheard as the patrons left the opera: "How did you enjoy Lucia di Labrador?"

"Shih Tzu."

Best, Don Bauder

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Psycholizard Feb. 22, 2010 @ 9:02 a.m.

to 29

How could I let that one slip my hook? Why is it no matter how many fish we catch, we think only of the pun that got away?

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Psycholizard Feb. 22, 2010 @ 9:19 a.m.

to 28

Gentlemen hail her as Paleolithic Goddess. In fairness, the people who really sing the MTV stuff are likely not beautiful, or they would learn the simple steps and dance it themselves. Shocking to find an arena that celebrates women for their talent rather than their looks.

As the 250 pound woman dies of consumption, our eyes are too blurred by tears to see anything but a delicate flower, petals blown in the wind. That is Art, a total fraud, but somehow more real than real.

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Don Bauder Feb. 22, 2010 @ 11:53 a.m.

Response to post #30: Maybe you let that fish off your hook because you really prefer meat. Therefore, you must love Strauss's "Salami," and stick up your nose at Bizet's "Pearl Fishers." One man's meat is another man's poisson. Best, Don Bauder

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Don Bauder Feb. 22, 2010 @ 11:57 a.m.

Response to post #31: The Chargers could use some of those 350 pound sopranos in their offensive line. Best, Don Bauder

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SDaniels Feb. 22, 2010 @ 2:51 p.m.

re: #26:

"There are things man was not meant to see."

For a velvet painting of pits playing poker? Nah. But for any of these, I'd paw out good money to see!

Pun o' th' Year:

"One man's meat is another man's poisson."

By Don Bauder

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Psycholizard Feb. 22, 2010 @ 8:35 p.m.

to 34

Few realize that Poker Dogs is actually an icon of Puppyism, illustrating a terrifying prophecy of the Great Puppy. Some say it foretells a Wall Street collapse. Probably nonsense. One dog certainly looks like Ben Bernanke though.

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Psycholizard Feb. 22, 2010 @ 8:57 p.m.

to 33

The game might be more interesting if a woman played center.

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Don Bauder Feb. 22, 2010 @ 10:19 p.m.

Response to post #34: Get thee to a Punnery! Best, Don Bauder

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Don Bauder Feb. 22, 2010 @ 10:21 p.m.

Response to post #35: Bernanke's shortsightedness has certainly created some dogs in the stock market. And that's even though he cares about Wall Street, not Main Street. Best, Don Bauder

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Don Bauder Feb. 22, 2010 @ 10:22 p.m.

Response to post #36: Certainly it would be more interesting to a T formation quarterback. Best, Don Bauder

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SDaniels Feb. 23, 2010 @ 8:57 a.m.

re: #31

"As the 250 pound woman dies of consumption, our eyes are too blurred by tears to see anything but a delicate flower, petals blown in the wind. That is Art, a total fraud, but somehow more real than real."

This, psycholizard, is the perfect dissertation on opera, and almost changes my mind about putting the cape back on and jumping in!

Fact, I'm going to write an opera myself, with the following aria's refrain in mind:

'Paleo, Litheo, even if it's old Cro-, she's still Willendorf to meeeee.'

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Don Bauder Feb. 23, 2010 @ 2:10 p.m.

Response to post #40: I can hear it now. Old Crow or old Cro-? I assume, as in Crone. Instead of consumption, she has crone's disease? Best, Don Bauder

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Psycholizard Feb. 24, 2010 @ 12:32 a.m.

to 40

Dat Old Crow magnum, dat Old Crow magnum, got me tossed from the bus, as truly pithy cuss.

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Don Bauder Feb. 24, 2010 @ 7:20 a.m.

Response to post #42: That's your Crow magnum opus. Best, Don Bauder

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Don Bauder Feb. 24, 2010 @ 7:25 a.m.

Response to post #43: Have we gone from dog operas to bird operas now? Can I start? Cavalleria Roostercana. Best, Don Bauder

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Duhbya Feb. 24, 2010 @ 11:04 a.m.

Re #45:

Uhoh...here we go.

The Drake's Progress

Kingfisher Roger

Dodo and Aeneas

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Psycholizard Feb. 24, 2010 @ 12:40 p.m.

to 45

Birds squawk at the idea of lip syncing our operas when they have a full repertory of their own, ranging from the tragic Toss Caw and Partridge Fall, to the comic Swallow Me and Loon Grin. Shows are usually free, but in the Summer they sometimes perform an outdoor Tern Dough to raise money.

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Don Bauder Feb. 24, 2010 @ 3:21 p.m.

Response to post #46: There is already at least one opera based on a bird: Rossini's Thieving Magpie. How about Richard Strauss's Swallowme? Or Johann Strauss's Die Fledertitmouse? Or Mozart's Cosi fan Tuftedtitmouse? Best, Don Bauder

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Don Bauder Feb. 24, 2010 @ 3:38 p.m.

Response to post #47: How about Verdi's Erne-ani? Or Handel's Rode-runner? Of course, there is already Rimsky-Korsakov's Golden Cockerel. One time I was dared to make a pun out of Rimsky-Korsakov. This is what I came up with: There was a Russian with a terrible affliction: every time he dreamed of winter sporting equipment, he had violent coughing fits. He was cured by a psychiatrist. He was explaining his past problem: "When I'd dream skate, I cough. When I'd dream sled, I cough. When I'd Rimsky-Korsakov." Best, Don Bauder

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SDaniels Feb. 24, 2010 @ 3:48 p.m.

Duhbya stole my only contribution with Kingfisher, so...

My vote? Goes to: Mozart's Cosi fan Tuftedtitmouse!

re: #41: Old Cro--, as in "Cromagnon," in keeping with my Paleopuntastic pitch for an opera.

Mr. Bauder, Ho no, old Cro! I do have Crone's (really, Crohn's) disease. While happily, it does not age me overly, it allows me to hang out at home and on the Reader site, far more than the doctor would prescribe.

Now don't:

Crow me a river, Cause I crowed a river fuh yooooou ;)

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SDaniels Feb. 24, 2010 @ 3:50 p.m.

And where is SurfPuppy, who must be a connoisseur of bird fare? Off chasing a double-breasted mattress thrasher?

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Don Bauder Feb. 24, 2010 @ 8:29 p.m.

Response to post #50: A kind of black bird is an ani, which you probably wouldn't know unless you do crossword puzzles. Ergo, Verdi features two birds in one opera: "Erne-ani." Best, Don Bauder

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Don Bauder Feb. 24, 2010 @ 8:31 p.m.

Response to post #51: Do you suppose SurfPuppy will duck this one? Or simply parrot what others have said? Best, Don Bauder

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