When you hear hoofbeats, think horses, not zebras, it’s an often-repeated med-school axiom that means consider the simple solution first. Dr. Clarence "Joe” Gibbs, Jr., a researcher at the National Institutes of Health (NIH), hears ...
Figure 1. Human Immunodeficiency virus (HIV) can live within the body for up to 15 years without causing disease. Figure 2 (A) To go forth and multiply, HIV fuses with Immune cells called macrophages and T4 lymphocytes. (B) A glycoprotein on HIVs surface, gpl 20. first snaps Into CD4. a protein on the surface of these Immune cells. (Q The gafflike gp41 then springs out from under gpl20 and hooks the Immune cell. (D) As the virus and cell fuse. HIV shoots Its core Into the cell, establishing an HIV Infection that will eventually lead to AIDS.
Posted November 30, 1989
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Joe Gibbs and Jonas Salk are counting on the chimpanzees