Masters of the Universe (aka Mastas of the Universe) has been around since the early 1990s. The lineup has included at various times rapper and producer Michael Quiñones (aka Scatter Brain the Acid Atheist), his older brother Frankie Quiñones (aka Odessa Kane), as well as former local Gonjasufi, and Genghis Khan, with whom Michael Quiñones produced an album called Night Gallery in 2012.

The 1994 Mastas release Microcrusifiction features Orko the Sycotik Alien and Odessa Kane (then known as Matrix).

Michael Quiñones provided beats for the 2003 Masters of the Universe full-length Nephlim Modulation Systems. Around the same time, he cofounded Kilowattz with Gonjasufi and instrumental beat duo Skrapez, releasing a full-length called Wrought of Chaos.

As of 2015, the Masters included Orko Elohiem, Autopsy, West Kraven, Delon Deville, Bennie
Herron aka Eklipse, Jahsun Edmonds aka Millenium, Bass Blak, Phenom, Zombie Nightstalker, Enigmatic, DJ Third Rail, Johaz, Authentik, Mike Swift, Taylor Tosh, Nobaze, and Kontroversial Black.